.In the 1960s, US anatomist Leonard Hayflick noticed that replicative cells possess a minimal number of divisions, triggered in part by telomere lessening and later on termed the Hayflick limitation. He observed that some tissues ceased portioning but rejected to die, a process called senescence that has actually since been actually linked in several ailments and also is now being actually targeting through biotech and pharmaceutical companies.The Clinical Pipeline is a column on translational and also clinical investigation, from seat to bedside.